Identification | Back Directory | [Name]
EAD1 HCl | [CAS]
1644388-26-0 | [Synonyms]
EAD1 HCl EAD1(free base) 1,2-Ethanediamine, N1-[2-[[[1-[(4-chlorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]amino]ethyl]-N2-(7-chloro-4-quinolinyl)-N1-methyl- | [Molecular Formula]
C24H27Cl2N7 | [MDL Number]
MFCD34184735 | [MOL File]
1644388-26-0.mol | [Molecular Weight]
484.42 |
Hazard Information | Back Directory | [Uses]
EAD1 is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 also induces apoptosis[1]. | [References]
[1] Lars Ulrik Nordstr?m, et al. Discovery of Autophagy Inhibitors With Antiproliferative Activity in Lung and Pancreatic Cancer Cells. ACS Med Chem Lett. 2015 Jan 8;6(2):134-9. DOI:10.1021/ml500348p |
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