ChemicalBook--->CAS DataBase List--->1644388-26-0

1644388-26-0

1644388-26-0 Structure

1644388-26-0 Structure
IdentificationBack Directory
[Name]

EAD1 HCl
[CAS]

1644388-26-0
[Synonyms]

EAD1 HCl
EAD1(free base)
1,2-Ethanediamine, N1-[2-[[[1-[(4-chlorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]amino]ethyl]-N2-(7-chloro-4-quinolinyl)-N1-methyl-
[Molecular Formula]

C24H27Cl2N7
[MDL Number]

MFCD34184735
[MOL File]

1644388-26-0.mol
[Molecular Weight]

484.42
Chemical PropertiesBack Directory
[Boiling point ]

687.5±65.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[pka]

8.41±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

EAD1 is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 also induces apoptosis[1].
[References]

[1] Lars Ulrik Nordstr?m, et al. Discovery of Autophagy Inhibitors With Antiproliferative Activity in Lung and Pancreatic Cancer Cells. ACS Med Chem Lett. 2015 Jan 8;6(2):134-9. DOI:10.1021/ml500348p
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