| Identification | More | [Name]
7-Fluoro-4-quinazolone | [CAS]
16499-57-3 | [Synonyms]
7-FLUOROQUINAZOLIN-4-OL
BUTTPARK 76\07-32 | [Molecular Formula]
C8H5FN2O | [MDL Number]
MFCD05664874 | [Molecular Weight]
164.14 | [MOL File]
16499-57-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
246.0 to 250.0 °C | [Boiling point ]
293.3±42.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
0.51±0.20(Predicted) | [color ]
White to Gray to Red | [InChI]
InChI=1S/C8H5FN2O/c9-5-1-2-6-7(3-5)10-4-11-8(6)12/h1-4H,(H,10,11,12) | [InChIKey]
KCORZHJVTZIZFD-UHFFFAOYSA-N | [SMILES]
N1C2=C(C=CC(F)=C2)C(=O)NC=1 | [CAS DataBase Reference]
16499-57-3(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
7-Fluoro-4-quinazolone is a fluorinated quinazolin-4(3H)-one with poly(ADP-ribose)polymerase-1 (PARP-1) inhibitory activity.It is also used as an intermediate in the preparation of the aurora kinase inhibitor AZD1152 (A808100).
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