| Identification | Back Directory | [Name]
2H-Indol-2-one,1,3-dihydro-1-methyl-5-[[4-[(2S,4R)-tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl]-2-thienyl]thio]- | [CAS]
166882-70-8 | [Synonyms]
ZD 4407
AZD 4407
2H-Indol-2-one,1,3-dihydro-1-methyl-5-[[4-[(2S,4R)-tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl]-2-thienyl]thio]- | [Molecular Formula]
C19H21NO3S2 | [MDL Number]
MFCD00934648 | [MOL File]
166882-70-8.mol | [Molecular Weight]
375.5 |
| Chemical Properties | Back Directory | [Boiling point ]
665.6±55.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
13.68±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
AZD 4407 is a potent 5-lipoxygenase inhibitor. | [IC 50]
5-Lipoxygenase | [References]
[1] Jonathan Hutton, et al. Use of a Titanium Thienyl Anion and a Simple Procedure for Introducing a Thiol Group into Thiophene in the Development of a Manufacturing Route to the 5-Lipoxygenase Inhibitor ZD4407. Org Process Res Dev. 1997 Jan 15;1(1): 61–67. |
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