| Identification | Back Directory | [Name]
dl-Cathinone Hydrochloride | [CAS]
16735-19-6 | [Synonyms]
dl-Cathinone Hydrochloride
HPZCAKYHISJOIK-UHFFFAOYSA-N
α-Aminopropiophenone Hydrochloride
Propiophenone, 2-amino-, hydrochloride
"Cathinone hydrochloride, racemic mixture"
2-amino-1-phenylpropan-1-one hydrochloride
2-amino-1-phenyl-propan-1-one hydrochloride
1-Propanone, 2-amino-1-phenyl-, hydrochloride
DL-Cathinone (hydrochloride) (exempt preparation) | [Molecular Formula]
C9H12ClNO | [MOL File]
16735-19-6.mol | [Molecular Weight]
185.651 |
| Chemical Properties | Back Directory | [Melting point ]
185-189 °C | [solubility ]
DMF: 20 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
Cathinone, the main psychoactive alkaloid from the khat plant (C. edulis), is a potent central stimulant and a naturally occurring analog of amphetamine. Cathinone, the main psychoactive alkaloid from the khat plant (C. edulis), is a potent central stimulant and a naturally occurring analog of amphetamine. DL-Cathinone is a racemic mixture of (−)-(S)-cathinone (Item No. 13869) and its less potent (+)-isomer.1 Like amphetamine, DL-cathinone and (−)-(S)-cathinone are potent releasers of norepinephrine and dopamine.2,3,4 With an ED50 value of 0.24 mg/kg, DL-cathinone produces amphetamine-like effects on the operant behavior of rats trained to discriminate 0.2-0.8 mg/kg of (D)-amphetamine.4 This product is intended for research and forensic applications. | [Description]
Cathinone, the main psychoactive alkaloid from the khat plant (C. edulis), is a potent central stimulant and a naturally occurring analog of amphetamine. DL-Cathinone is a racemic mixture of (−)-(S)-cathinone (Item No. 13869) and its less potent (+)-isomer.1 Like amphetamine, DL-cathinone and (−)-(S)-cathinone are potent releasers of norepinephrine and dopamine.2,3,4 With an ED50 value of 0.24 mg/kg, DL-cathinone produces amphetamine-like effects on the operant behavior of rats trained to discriminate 0.2-0.8 mg/kg of (D)-amphetamine.4 This product is intended for research and forensic applications. | [Uses]
Racemic Cathinone (C225700), a psychoactive alkaloid found in the leaves of the khat plant. Cathinone is chemically similar to ephedrine and amphetamines and is known to exhibit antidepressant propert
ies. | [References]
[1] TERRY A DAL CASON Richard A G Richard Young. Cathinone: An Investigation of Several N-Alkyl and Methylenedioxy-Substituted Analogs[J]. Pharmacology Biochemistry and Behavior, 1997, 58 4: Pages 1109-1116. DOI: 10.1016/s0091-3057(97)00323-7
[2] PETER KALIX Richard A G. Further evidence for an amphetamine-like mechanism of action of the alkaloid cathinone[J]. Biochemical pharmacology, 1986, 35 18: Pages 3015-3019. DOI: 10.1016/0006-2952(86)90380-1
[3] RICHARD A. GLENNON Stephen M L. Serotonin receptor affinity of cathinone and related analogs[J]. Journal of Medicinal Chemistry, 1982, 25 4: 393-397. DOI: 10.1021/jm00346a012
[4] MARTIN D. SCHECHTER Richard A G John A Rosecrans. Comparison of behavioral effects of cathinone, amphetamine and apomorphine[J]. Pharmacology Biochemistry and Behavior, 1984, 20 2: Pages 181-184. DOI: 10.1016/0091-3057(84)90238-7 |
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