ChemicalBook--->CAS DataBase List--->1686149-74-5

1686149-74-5

1686149-74-5 Structure

1686149-74-5 Structure
IdentificationBack Directory
[Name]

BMS-589154)
[CAS]

1686149-74-5
[Synonyms]

BMS-591329
BMS-719288
BMS-724914
BMS-728626
BMS-778960
Apixaban-9
BMS-589154)
BMS-589154))
Apixaban IMP
Apixaban Impurity I
5''''-Methyl-apixaban
Impurity of apixaban375
Apixaban Amino acid impurity
Apixaban iMpurity(BMS-591455
Apixaban amino acid impurities
Apixaban Impurity BMS-591455-01
Apixaban Impurity 10(BMS-728626-01)
(Z)-1-(4-methoxyphenyl)-4-(2-(4-methoxyphenyl)hydrazono)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxamide
3-acetyl-1-(4-methoxyphenyl)-6-(4-(2-oxopiperidin-1-yl)phenyl)-1,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridin-7-one
1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopyrrolidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
6-(4-((4-carboxybutyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-
1-(4-methoxyphenyl)-3-(morpholine-4-carbonyl)-6-(4-(2-oxopiperidin-1-yl)phenyl)-1,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridin-7-one
Apixaban impurity 6/Apixaban Amino Acid Impurity/4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
[Molecular Formula]

C26H27N5O4
[MDL Number]

MFCD27996061
[MOL File]

1686149-74-5.mol
[Molecular Weight]

473.52
Chemical PropertiesBack Directory
[Boiling point ]

766.0±60.0 °C(Predicted)
[density ]

1.39±0.1 g/cm3(Predicted)
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

15.01±0.20(Predicted)
[color ]

White to Off-White
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Uses]

An analytical standard impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
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