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503615-03-0

503615-03-0 Structure

503615-03-0 Structure
IdentificationBack Directory
[Name]

3-(4-Morpholinyl)-1-(4-nitrophenyl)-5,6-dihydro-2(1H)-pyridinone
[CAS]

503615-03-0
[Synonyms]

Apixaban Impurity 19
Apixaban Intermediate3
5-morpholin-4-yl-1-(4-nitrophenyl)-2,3-dihydropyridin-6-one
3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
3-(4-Morpholinyl)-1-(4-nitrophenyl)-5,6-dihydro-2(1H)-pyridinone
5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone
3-(Morpholin-4-yl)-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one (Nitro MPDP)
[Molecular Formula]

C15H17N3O4
[Molecular Weight]

303.313
[MOL File]

503615-03-0.mol
Chemical PropertiesBack Directory
[Boiling point ]

506.5±50.0 °C(Predicted)
[density ]

1.356
[storage temp. ]

Sealed in dry,Store in freezer, under -20°C
[pka]

3.11±0.20(Predicted)
Questions And AnswerBack Directory
[Description]

3-(4-Morpholinyl)-1-(4-nitrophenyl)-5, 6-dihydro-2(1H)-pyridinone is the intermediate for the synthesis of apixaban, which is an anticoagulant for the treatment of venous thromboembolic events. 
[References]

Chao, H. E., et al. "Synthesis of Apixaban." Chinese Journal of Pharmaceuticals (2014).
https://en.wikipedia.org/wiki/Apixaban
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