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1687735-82-5

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1687735-82-5 Structure

1687735-82-5 Structure
IdentificationBack Directory
[Name]

2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)-
[CAS]

1687735-82-5
[Synonyms]

Aldose reductase-IN-2
2-Propenamide, N-[3-[[(2R)-2-(acetylamino)-1-oxo-3-(phenylmethoxy)propyl]amino]propyl]-2-cyano-3-(4-hydroxyphenyl)-, (2E)-
[Molecular Formula]

C25H28N4O5
[MOL File]

1687735-82-5.mol
[Molecular Weight]

464.51
Chemical PropertiesBack Directory
[Boiling point ]

841.1±65.0 °C(Predicted)
[density ]

1.247±0.06 g/cm3(Predicted)
[pka]

9.20±0.26(Predicted)
Hazard InformationBack Directory
[Uses]

Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR). Aldose reductase-IN-2 has antioxidation capacity. Aldose reductase-IN-2 is a promising anti-diabetic complications agent[1].
[References]

[1] Liu Y, et al. Enhanced antioxidation capacity endowed to a mixed type aldose reductase inhibitor leads to a promising anti-diabetic complications agent [published online ahead of print, 2022 Jan 17]. Bioorg Chem. 2022;120:105624. DOI:10.1016/j.bioorg.2022.105624
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Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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1687735-82-5