| Identification | More | [Name]
1-METHYL-PIPERIDINE-3-CARBOXYLIC ACID METHYL ESTER | [CAS]
1690-72-8 | [Synonyms]
1-METHYL-PIPERIDINE-3-CARBOXYLIC ACID METHYL ESTER
METHYL 1-METHYLPIPERIDINE-3-CARBOXYLATE
1-methyl-3-piperidinecarboxylicacimethylester
1-methylnipecoticacidmethylester
1-methyl-nipecoticacimethylester
dihydroarecoline
methyln-methylnipecotate
n-methyl-3-carbomethoxypiperidine
1-Methyl-3-Piperidinelarboxylate
1-Methyl-3-piperidinecarboxylic acid methyl ester | [EINECS(EC#)]
210-314-1 | [Molecular Formula]
C8H15NO2 | [MDL Number]
MFCD00128793 | [Molecular Weight]
157.21 | [MOL File]
1690-72-8.mol |
| Hazard Information | Back Directory | [Uses]
Methyl 1-methylpiperidine-3-carboxylate belongs to the class of organic compounds known as piperidinecarboxylic acids. Piperidinecarboxylic acids are compounds containing a piperidine ring with a carboxylic acid group. Methyl 1-methylpiperidine-3-carboxylate is a strong basic compound (based on its pKa). It could be used to synthesize (1-methylpiperidin-3-yl)methanol. The specific steps are shown as follows: into a 500 mL round bottom flask containing a solution of methyl 1-methylpiperidine-3- carboxylate (12.0 g, 76 mmol) in tetrahydrofuran (500 mL) was added lithium aluminumhydride (4.3 g, 114 mmol) in portions at 0 °C. The reaction mixture was stirred at room temperature for 1 h. The reaction was quenched with methanol at 0 °C, and the precipitated solid was filtered through celite. The filtrate was concentrated and the crude was purified by flash chromatography eluting with methanol in dichloromethane (5-10percent) to afford (1-methylpiperidin-3-yl)methanol as a solid.
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