| Identification | Back Directory | [Name]
Bucladesine | [CAS]
16980-89-5 | [Synonyms]
DC 2797
,5Õ
DBcAMP-Na
N6-2Õ
Prestwick_32
CAMP, DB-, NA
BUCLADESINE NA
DIB-3:5-CAMP, NA
dt5621sodiumsalt
DIBUTYRYL-CAMP NA
bucladesinesodium
Sodium bucladesine
Dibutyacyladenosine
DIBUTYRYL-CYCLICAMP
sodiumdibutyrylcamp
DB-CAMP SODIUM SALT
BucladesineSodiumSal
Dibutyryl-cAMP, sodi
Bucladesine USP/EP/BP
dibutylcampsodiumsalt
dibutylcyclicampsodium
BUCLADESINE SODIUM SALT
ibutyryl cyclic AMP sodium
dibutylcyclicampsodiumsalt
Dibutyryl cyclic AMP sodium
DIBUTYRYL-CAMP, SODIUM SALT
monosodiumdibutyrylcyclicamp
Dibutyryl-cAMP (Bucladesine)
N6,2′-O-Dibutyryladenosine 3′
sodiumdibutyryl3’,5’-cyclicamp
-O-Dibutyryl-adenosine 3Õ
e,butyrate(ester),monosodiumsalt
DIBUTYRYL CYCLIC AMP SODIUM SALT
Dibutyacyladenosine cyclphosphate
Dibutyryl-cAMP sodium salt, >=98%
N6,2'-O-dibutyryl cAMP sodium salt
Dibutyryl-cAMP (Bucladesine sodium)
Bucladesine, Dibutyryl cyclic-AMP
Dibutyryl cyclic AMP monosodium salt
Dibutyryl 3',5'-cyclic AMP sodium salt
-cyclophosphate sodium salt monohydrate
N6.2-O-dibutyryladenosine-3.5-cyclic(+4℃)
Sodium dibutyryl adenosine cyclophosphate
Adenosine 3?,5?-cyclic Monophosphate, N?,O
Calcium Dibutyacyladenosine Cyclophosphate
N6,O2'-Dibutyryl-3',5'-cyclic AMP sodium salt
N6,2'-O-Dibutyryl-3',5'-cyclic AMP sodium salt
N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHA
4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.
N6,O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE NA
Sodium N6,2'-O-dibutyryladenosine 3',5'-cyclic phosphate
N6,O2'-DIBUTYRYLADENOSINE-3':5'-PHOSPHATE CYCLIC NA-SALT
N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLO-P HOSPHATE SO-SALT
N,2'-O-Dibutyryladenosine-3',5'-phosphoric acid sodium salt
n6,02’-dibutyryladenosine3’,5’-cyclicmonophosphatesodiumsalt
N6,O2'-DIBUTYRYLADENOSINE-3',5'-PHOSPHATE CYCLIC SODIUM SALT
2'-O-Dibutyryladenosine 3',5'-cyclic Monophosphate sodiuM salt
N,2'-O-Dibutanoyladenosine 3',5'-(phosphoric acid sodium) salt
N6,2'-O-Dibutyryladenosine-3',5'-monophosphate monosodium salt
N6,2'-O-DIBUTRYL-ADENISINE-3',5'-CYCLICMONPHOSPHATE SODIUM SALT
N6, O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE SODIUM SALT
N6,2'-O-Dibutyryladenosine3',5'-CyclicMonophosphateSodiumSalt>
N6,O2'-DIBUTYRYL ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
N-6,O-2'-Dibutyryladenosine cyclic 3',5'-monophosphate sodium salt
N6,2'-O-DIBUTYRYLADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM
ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6,O2'-DIBUTYRYL-, SODIUM SALT
dc2797 , sodium dibutyryl camp , dibutyryl-camp sodium salt , dbcamp
N6, 2'-O-Dibutyryadenosine 3',5'-cyclic monophosphate sodium salt, 96%
BUCLADESINE[N-6,O-2''-DIBUTYRYL ADENOSINE CYCLIC 3'',5''-MONOPHOSPHATE]
n6,2’-o-dibutyryladenosine-3’,5’-cyclicmonophosphate(dbcamp),sodiumsalt
n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-butyramidcyclichydrogenphosphat
ADENOSINE-3',5'-CYCLIC MONOPHOSPHORIC ACID, N,2'O-DIBUTYRYL, SODIUM SALT
adenosine,n-(1-oxobutyl)-,cyclic3’,5’-(hydrogenphosphate)-2’-butanoate,m
Adenosine,N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate,
N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt, ≥97% (HPLC)
N-(1-Oxobutyl)adenosine cyclic 3',5'-(hydrogen phosphate)2'-butanoate sodium salt
N6,2μ-O-Dibutyryladenosine 3μ,5μ-cyclic monophosphate monohydrate sodium salt
Bucladesine Sodium Salt / Dibutyryl Adenosine Cyclophosphate Sodium Salt（DB-cAMP. Na）
Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, monosodium salt
Adenosine,N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, sodiuM salt(1:1)
Adenosine 3,5-cyclic Monophosphate, N,O2-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem
Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt
butyramide,n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-,cyclichydrogenphosphate,butyrate(ester),monosodiumsalt
Butyramide, N-(9-b-D-ribofuranosyl-9H-purin-6-yl)-, cyclic hydrogen phosphate butyrate (ester), monosodium salt (8CI) | [EINECS(EC#)]
241-059-4 | [Molecular Formula]
C18H23N5NaO8P | [MDL Number]
MFCD00005843 | [MOL File]
16980-89-5.mol | [Molecular Weight]
491.37 |
| Chemical Properties | Back Directory | [Melting point ]
>173°C (dec.) | [storage temp. ]
−20°C
| [solubility ]
H2O: 50 mg/mL
| [form ]
powder
| [color ]
white
| [Merck ]
14,1463 | [Stability:]
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month. |
| Hazard Information | Back Directory | [Description]
Bucladesine sodium is a derivative of cyclic-AMP with cardiac stimulant and
peripheral vasodilatory properties. It is reported to be useful in cardiac
insufficiency, especially after heart surgery. | [Originator]
Daiichi Seiyaku; Seishin Seiyaku (Japan) | [Uses]
An analog of cyclic AMP that stimulates cAMP-dependent protein kinase | [Uses]
Cardiotonic;Adenylate cyclase modulator | [Application]
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt has been used:
as a medium supplement for neural crest stem cells (NCSCs) differentiation
as a component of thawing medium for cryopreserved human iPSC (induced pluripotent stem cell)-derived neurons
in serum-free Dulbecco′s modified eagle′s medium (DMEM) to induce astrocyte differentiation | [Definition]
ChEBI: Bucladesine sodium is a 3',5'-cyclic purine nucleotide. | [Brand name]
ACTOCIN | [General Description]
A cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Causes an increase in the steady state level of parathyroid hormone-related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells. | [Biological Activity]
Cell-permeable analog of cAMP; activates cAMP-dependent protein kinases. | [Biochem/physiol Actions]
Cell-permeable cAMP analog that activates cAMP dependent protein kinase (PKA). | [storage]
Store at -20°C | [References]
1) Bartsch?et al.?(2003),?Bioactivatable, membrane-permeant analogs of cyclic nucleotides as biological tools for growth control of C6 glioma cells; Biol. Chem.,?384?1321
2) Carranza?et al.?(1998),?Protein kinase A induces recruitment of active Na+,K+-ATPase units to the plasma membrane of rat proximal convoluted tubule cells; J. Physiol.,?15?511
3) Hei?et al.?(1991),?Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs; Mol. Pharmacol.,?39?233
4) Imamura?et al.?(1998),?Differential expression of dystrophin isoforms and utrophin during dibutyryl-cAMP-induced morphological differentiation of rat brain astrocytes; Proc. Natl. Acad. Sci. USA,?95?6139
5) Xia?et al.?(2016),?Transcriptional comparison of human induced and primary midbrain dopaminergic neurons; Sci. Rep.,?6?20270 |
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