| Identification | Back Directory | [Name]
Nonabine | [CAS]
16985-03-8 | [Synonyms]
Nonabine
7-(1,2-dimethylheptyl)-2,2-dimethyl-4-(4-pyridyl)chromen-5-ol
2,2-dimethyl-7-(3-methyloctan-2-yl)-4-pyridin-4-ylchromen-5-ol
2,2-dimethyl-7-(3-methyloctan-2-yl)-4-pyridin-4-yl-chromen-5-ol
2,2-Dimethyl-7-(3-methyloctan-2-yl)-4-(pyridin-4-yl)-2H-chromen-5-ol
2H-1-Benzopyran-5-ol, 7-(1,2-dimethylheptyl)-2,2-dimethyl-4-(4-pyridinyl)- | [Molecular Formula]
C25H33NO2 | [MDL Number]
MFCD00865549 | [MOL File]
16985-03-8.mol | [Molecular Weight]
379.541 |
| Hazard Information | Back Directory | [Uses]
Nonabine (BRL-4664), a cannabinoid, is a antiemetic agent. Nonabine activates CB1 receptor in
the brainstem and enteric nervous system[1][2]. | [IC 50]
CB1 | [References]
[1] Archer CB, et al. Antiemetic effect of nonabine in cancer chemotherapy: a double blind study comparing nonabine and chlorpromazine. Br Med J (Clin Res Ed). 1983 Jan 29;286(6362):350-1. DOI:10.1136/bmj.286.6362.350-a
[2] Shah S, et al. ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids. Reg Anesth Pain Med. 2023 Mar;48(3):97-117. DOI:10.1136/rapm-2022-104013 |
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