| Identification | More | [Name]
3-Fluorobenzoyl chloride | [CAS]
1711-07-5 | [Synonyms]
3-FLUOROBENZOYL CHLORIDE
AKOS BBS-00003915
M-FLUOROBENZOYL CHLORIDE
3-Fluorobenzoxyl chloride
3-fluoro-benzoylchlorid
Benzoyl chloride, m-fluoro-
fluorobenzoylchloride
meta-Fluorobenzoyl chloride
m-Fluorobenzoic acid chloride
3-Fluorobenzoyl Chloride m-Fluorobenzoyl Chloride
m-Fluorobenzoyl
Benzoyl chloride, 3-fluoro-
3-Fluorobenzoylchloride98% | [EINECS(EC#)]
216-977-3 | [Molecular Formula]
C7H4ClFO | [MDL Number]
MFCD00000670 | [Molecular Weight]
158.56 | [MOL File]
1711-07-5.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to light yellow liquid | [Melting point ]
-30 °C (lit.) | [Boiling point ]
189 °C (lit.) | [density ]
1.304 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.529(lit.)
| [Fp ]
180 °F
| [storage temp. ]
Store below +30°C. | [form ]
Liquid | [color ]
Clear colorless to light yellow | [Sensitive ]
Lachrymatory | [Detection Methods]
GC,NMR | [BRN ]
636610 | [InChI]
InChI=1S/C7H4ClFO/c8-7(10)5-2-1-3-6(9)4-5/h1-4H | [InChIKey]
SYVNVEGIRVXRQH-UHFFFAOYSA-N | [SMILES]
C(Cl)(=O)C1=CC=CC(F)=C1 | [CAS DataBase Reference]
1711-07-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzoyl chloride, 3-fluoro-(1711-07-5) | [Storage Precautions]
Moisture sensitive | [EPA Substance Registry System]
1711-07-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R37:Irritating to the respiratory system.
R36/37:Irritating to eyes and respiratory system .
R14:Reacts violently with water. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [F ]
19 | [Hazard Note ]
Corrosive/Lachrymatory | [TSCA ]
T | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29163900 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Eye Dam. 1
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to light yellow liquid | [Uses]
3-Fluorobenzoyl chloride was used in synthesis of 4-[18F]fluoro-N-[2-[1-(2-methoxyphenyl)-1-piperazinyl]ethyl-N-2-pyridinyl-benzamide by radiosynthesis. It was also used as reagent in one-pot synthesis of N-(1,3-diphenyl-1H-pyrazol-5-yl)amides. It was used in three phase hollow fiber liquid-phase microextraction with in situ derivatization method coupled with HPLC-UV for the determination of metformin hydrochloride in biological fluids. | [Synthesis]
146 mg (1.2 mmol) of m-fluorobenzoic acid was taken in a dry 25 mL round-bottomed flask, 10 mL of anhydrous dichloromethane was added, then 0.13 mL (1.8 mmol) of dichlorosulfoxide was added, heated and refluxed for 2 h. The dichloromethane and the excess |
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