| Identification | More | [Name]
3-Chloro-6-hydrazinopyridazine | [CAS]
17284-97-8 | [Synonyms]
1-(6-CHLOROPYRIDAZIN-3-YL)HYDRAZINE
3-CHLORO-6-HYDRAZINOPYRIDAZINE
(3-CHLOROPYRIDAZIN-6-YL)HYDRAZINE
(6-CHLORO-PYRIDAZIN-3-YL)-HYDRAZINE
AKOS BBS-00000699
BUTTPARK 97\15-14
RARECHEM BG FB 0135
(3-Chloropyridazin-6-yl)hydrazine, tech
6-Chloro-3-pyridazinylhydrazine
3-Chloro-6-hydrazinopyridazine, HPLC 97%
3-Chloro-6-hydrazinylpyridazine
1-(6-Chloropyridazine-3-yl)hydrazine
3-Hydrazino-6-chloropyridazine | [Molecular Formula]
C4H5ClN4 | [MDL Number]
MFCD00051740 | [Molecular Weight]
144.56 | [MOL File]
17284-97-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
137-141 °C (lit.) | [Boiling point ]
271.0±23.0 °C(Predicted) | [density ]
1.63±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [form ]
powder | [pka]
5.34±0.20(Predicted) | [color ]
Off-white | [BRN ]
125591 | [InChI]
InChI=1S/C4H5ClN4/c5-3-1-2-4(7-6)9-8-3/h1-2H,6H2,(H,7,9) | [InChIKey]
FXYQRYGWWZKUFV-UHFFFAOYSA-N | [SMILES]
C1(Cl)=NN=C(NN)C=C1 | [CAS DataBase Reference]
17284-97-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R41:Risk of serious damage to eyes.
R43:May cause sensitization by skin contact. | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2928009090 |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 3-chloro-6-hydrazinopyridazine from 3,6-dichloropyridazine: 3,6-dichloropyridazine (3 g, 20.14 mmol) was reacted with hydrazine monohydrate (1 g, 20.14 mmol) in a sealed tube at 80 °C for 5 hours. After completion of the reaction, the solvent was removed by evaporation and the resulting crude product was used directly in the next step of the reaction without further purification (Yield: 3.56 g, Yield: 100%). The product [MH]+ was analyzed by liquid chromatography-mass spectrometry (LCMS, Method B) with m/z of 145.1 and retention time (tR) of 0.57 min. | [References]
[1] Patent: WO2011/18454, 2011, A1. Location in patent: Page/Page column 62-63
[2] Patent: WO2011/20861, 2011, A1. Location in patent: Page/Page column 67
[3] MedChemComm, 2014, vol. 5, # 4, p. 540 - 546
[4] Bulletin of the Korean Chemical Society, 2018, vol. 39, # 7, p. 853 - 857
[5] Patent: KR2018/94194, 2018, A. Location in patent: Paragraph 0221; 0222; 0223; 0224 |
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