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17388-80-6

17388-80-6 Structure

17388-80-6 Structure
IdentificationBack Directory
[Name]

N-Succinyl-5-aMinoiMidazole-4-carboxaMide Ribose
[CAS]

17388-80-6
[Synonyms]

N-Succinyl-5-aMinoiMidazole-4-carboxaMide Ribose
N-(5-Amino-1-ribosyl-4-imidazolecarbonyl)-L-aspartic acid
N-Succinyl-5-aMinoiMidazole-4-carboxaMide Ribose DisodiuM Salt
N-[5-Amino-1-(beta-D-ribofuranosyl)imidazole-4-carbonyl]-L-aspartic acid
N-[(5-AMino-1-β-D-ribofuranosyl-1H-iMidazol-4-yl)carbonyl]-L-aspartic Acid
L-Aspartic acid, N-[(5-amino-1-β-D-ribofuranosyl-1H-imidazol-4-yl)carbonyl]-
[Molecular Formula]

C13H18N4O9
[MDL Number]

MFCD31563062
[MOL File]

17388-80-6.mol
[Molecular Weight]

374.3
Chemical PropertiesBack Directory
[Melting point ]

>205°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Water (Very Slightly, Heated)
[form ]

Solid
[color ]

White to Off-White
[biological source]

synthetic
Hazard InformationBack Directory
[Uses]

A metabolite of Purine. Purine metabolism by adenylosuccinasedeficient. Since adenosine is a potent inhibitor of neuronal function, depressing the release of several excitatory transmitters and causin g direct hyperpolarization of neurons, it was possible that the symptoms seen in adenylosuccinate lyase (ASase) deficient patients could reflect an interference of succinylpurines with neurotransmissi on.
[Uses]

N-Succinyl-5-aminoimidazole-4-carboxamide Ribose is used in the detection of adenylosuccinate lyase deficiency in infants and mice as it is seen as a significant indicator in autism diagnosis.
[IC 50]

Human Endogenous Metabolite
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