| Identification | Back Directory | [Name]
atrasentan | [CAS]
173937-91-2 | [Synonyms]
A-147627
atrasentan
(+)-A 127722
A127722, CID 5310990
Atrasentan (ABT-627)
(+)-A 127722; ABT-627; A 127722; ABT 627
(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid
(2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID
3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-, (2R,3R,4S)-
Atrasentan [2R,3R,4S]-2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-[[(N,N-dibutylamino)-carboxyl]methyl]pyrrolidine-3-carboxylic acid | [Molecular Formula]
C29H38N2O6 | [MDL Number]
MFCD00940177 | [MOL File]
173937-91-2.mol | [Molecular Weight]
510.62 |
| Chemical Properties | Back Directory | [Melting point ]
122-124° | [Boiling point ]
659.4±55.0 °C(Predicted) | [density ]
1.188±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
3.49±0.60(Predicted) | [color ]
Off-White |
| Hazard Information | Back Directory | [Uses]
Palliative treatment of bone pain due to
metastatic prostate cancer and disease progression (endothelin
(ETA) receptor antagonist). | [Definition]
ChEBI: Atrasentan is a member of pyrrolidines. |
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