| Identification | More | [Name]
CHROMONE-3-CARBOXALDEHYDE | [CAS]
17422-74-1 | [Synonyms]
3-CHROMONECARBALDEHYDE
3-FORMYLCHROMONE
4-OXO-4H-1-BENZOPYRAN-3-CARBOXALDEHYDE
4-OXO-4H-CHROMENE-3-CARBALDEHYDE
AKOS B022468
AKOS BBS-00006952
AURORA KA-4820
BUTTPARK 29\06-40
CHROMONE-3-CARBOXALDEHYDE
4H-1-Benzopyran-3-carboxaldehyde, 4-oxo-
3-Formyl-4H-1-benzopyran-4-one
4-Oxo-4H-1-benzopyran-3-carbaldehyde
KAN-104141 | [EINECS(EC#)]
241-451-5 | [Molecular Formula]
C10H6O3 | [MDL Number]
MFCD00014667 | [Molecular Weight]
174.15 | [MOL File]
17422-74-1.mol |
| Chemical Properties | Back Directory | [Appearance]
orange crystalline powder | [Melting point ]
151-153 °C (lit.) | [Boiling point ]
245.11°C (rough estimate) | [density ]
1.2135 (rough estimate) | [refractive index ]
1.4500 (estimate) | [storage temp. ]
Refrigerator (+4°C) | [form ]
Crystalline Powder | [color ]
Orange | [Sensitive ]
Air Sensitive | [BRN ]
472849 | [InChI]
InChI=1S/C10H6O3/c11-5-7-6-13-9-4-2-1-3-8(9)10(7)12/h1-6H | [InChIKey]
FSMYWBQIMDSGQP-UHFFFAOYSA-N | [SMILES]
C1OC2=CC=CC=C2C(=O)C=1C=O | [CAS DataBase Reference]
17422-74-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29329900 | [Storage Class]
11 - Combustible Solids |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Ethanol-->Phosphorus oxitrichloride-->N,N-Dimethylacetamide-->2'-Hydroxyacetophenone | [Preparation Products]
2-Hydroxybenzophenone-->CHROMONE-->6-Hydroxy-6,9,10,11-tetrahydro-chromeno[4,3-b]quinolin-8-one-->Hydrazinecarbothioamide, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]--->4H-1-Benzopyran-3-carboxaldehyde, 4-oxo-, 3-oxime-->Benzenesulfonic acid, 4-methyl-, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide-->1,3-dimethyl-5-[(4-oxo-4H-chromen-3-yl)methylidene]-1,3-diazinane-2,4,6-trione |
| Hazard Information | Back Directory | [Chemical Properties]
orange crystalline powder | [Uses]
3-Formylchromone may be used in the following studies:
- Preparation of library of novel (E)-3-(2-arylcarbonyl-3-(arylamino)allyl)-4H-chromen-4-ones, by three-component domino reactions with (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones and anilines under catalyst-free conditions.
- Facile and ecofriendly synthesis of new chromonyl chalcones.
- Synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones.
| [Synthesis Reference(s)]
Tetrahedron Letters, 14, p. 1995, 1973 DOI: 10.1016/S0040-4039(01)96102-7 | [General Description]
Electrospray ionization mass spectrometry (ESI-MS) of protonated 3-formylchromone (3-FC) shows loss of H2 as a major fragmentation route to yield a ketene cation, which on reaction with water forms a protonated carboxylic acid. The invivo salubrious effects of 3-FC against nitrosodiethylamine (NDEA) mediated early hepatocellular carcinogenesis has been investigated. Synthesis and characterization of 3-FC and its derivatives has been reported. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|