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174262-13-6

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174262-13-6 Structure

174262-13-6 Structure
IdentificationBack Directory
[Name]

SDZ285-428
[CAS]

174262-13-6
[Synonyms]

SDZ285-428
NVP-VID-400
SDZ 285428;SDZ-285428;SDZ285-428
[1,1'-Biphenyl]-4-carboxamide, 4'-chloro-N-[2-(1H-imidazol-1-yl)-2-phenylethyl]-
[Molecular Formula]

C24H20ClN3O
[MDL Number]

MFCD30738054
[MOL File]

174262-13-6.mol
[Molecular Weight]

401.89
Chemical PropertiesBack Directory
[Melting point ]

202-205°C
[Boiling point ]

651.246±55.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.212±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[storage temp. ]

-20°C, Inert atmosphere
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

13.479±0.46(predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

SDZ 285-428 is a selective inhibitor of CYP24 (24-hydroxylase).
[in vivo]

Specific inhibition of protozoan CYP51 can potentially provide treatment for human trypanosomiases[1].

[IC 50]

CYP51; Trypanosoma
Spectrum DetailBack Directory
[Spectrum Detail]

SDZ285-428(174262-13-6)1HNMR
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