| Identification | Back Directory | [Name]
BPIQ-I | [CAS]
174709-30-9 | [Synonyms]
BPIQ-I
N-(3-bromophenyl)-3-methylimidazo[4,5-g]quinazolin-8-amine
8-[(3-BROMOPHENYL)AMINO]-3-METHYL-3H-IMIDAZO[4,5-G]-QUINAZOLINE
8-[(3-BROMOPHENYL)AMINO]-3-METHYL-3H-IMIDAZO[4,5-GAMMA]-QUINAZOLINE | [Molecular Formula]
C16H12BrN5 | [MDL Number]
MFCD02179191 | [MOL File]
174709-30-9.mol | [Molecular Weight]
354.2 |
| Chemical Properties | Back Directory | [Boiling point ]
535.5±60.0 °C(Predicted) | [density ]
1.62±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml | [form ]
A crystalline solid | [pka]
5.12±0.50(Predicted) |
| Hazard Information | Back Directory | [Description]
BPIQ-I is a quinazoline that inhibits the tyrosine kinase activity of the epidermal growth factor receptor (IC50 = 0.025 nM). It can inhibit the growth of SKOV3 and MDA-468 tumor cell lines with EC50 values of 6.5 and 30 μM, respectively. |
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