| Identification | More | [Name]
4,4'-Dimethyldiphenylsulfoxide | [CAS]
1774-35-2 | [Synonyms]
4,4'-DIMETHYL DIPHENYL SULFOXIDE
4,4'-DIMETHYLDIPHENYLSULPHOXIDE
BENZENE, 1,1'-SULFINYLBIS[4-METHYL-]
DI-P-TOLYL SULFOXIDE
P-TOLYL SULFOXIDE
1,1’-sulfinylbis(4-methyl-benzen
1,1’-sulfinylbis-p-toluen
1-Methyl-4-[(4-methylphenyl)sulfinyl]benzene
4,4'-Ditolyl sulfoxide
Ditolyl sulfoxide
Ditolyl sulphoxide
ditolylsulfoxide
ditolylsulphoxide
p-Toluene, 1,1'-sulfinylbis-
Sulfoxide, ditolyl
sulfoxide,ditolyl
Toluene, 4,4'-sulfinylbis-
bis(p-tolyl)sulphoxide
Tolylsulfoxide
TolylSulphoxide98% | [EINECS(EC#)]
217-203-7 | [Molecular Formula]
C14H14OS | [MDL Number]
MFCD00008546 | [Molecular Weight]
230.33 | [MOL File]
1774-35-2.mol |
| Questions And Answer | Back Directory | [Uses]
4,4'-Dimethylbenzene sulfoxide (DMSO) is a sulfoxide compound. Representative marketed drugs containing a sulfoxide skeleton include esomeprazole (A. Aktiebolag, US5877192A, 1998), used to treat gastrointestinal disorders, and modafinil (LLLafon, US4927855A, 1990), used clinically to treat narcolepsy and anorexia. Due to their structural diversity and significant biological functions, the synthesis of sulfoxides has attracted widespread attention from organic synthetic chemists and pharmacologists. Furthermore, sulfoxide compounds possess important biological activities; by modifying their structure, their pharmacological activity can be enhanced, such as anti-ulcer, antiviral, anti-HIV-1, and antitumor effects. In the pesticide field, sulfoxide compounds offer advantages such as low dosage and low pollution as fungicides and herbicides. Sulfoxides, containing semi-polar groups, are neutral, soft-base extractants with a special affinity for noble metals in soft acids, resulting in high extraction rates and good selectivity. Furthermore, sulfoxides are important components of many natural products and pharmaceutical intermediates. Therefore, developing efficient and rapid methods for synthesizing sulfoxides is of great significance and remains a hot research area. |
| Safety Data | Back Directory | [WGK Germany ]
3
| [RTECS ]
XT4810000
| [HS Code ]
2930.90.2900 | [Storage Class]
11 - Combustible Solids | [Toxicity]
mouse,LD50,intraperitoneal,600mg/kg (600mg/kg),International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. Vol. 3, Pg. 41, 1961. |
| Hazard Information | Back Directory | [Synthesis]
In a 15mL reaction tube, p-methylbenzene azomethine sulfone 1b (0.6mmol), p-methylbenzenethiol 2b (0.2mmol), acetonitrile 1mL and water 1mL were added sequentially, mixed uniformly, and then stirred and reacted under the irradiation of 3W blue LED ligh |
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