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1776115-10-6

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1776115-10-6 Structure

1776115-10-6 Structure
IdentificationBack Directory
[Name]

BMS 986188
[CAS]

1776115-10-6
[Synonyms]

BMS 986188
9-(4-(2-bromobenzyloxy)phenyl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione
1H-Xanthene-1,8(2H)-dione, 9-[4-[(2-bromophenyl)methoxy]phenyl]-3,4,5,6,7,9-hexahydro-3,3,6,6-tetramethyl-
[Molecular Formula]

C30H31BrO4
[MDL Number]

MFCD34565177
[MOL File]

1776115-10-6.mol
[Molecular Weight]

535.47
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 1mg/mL; DMF:PBS (pH 7.2) (1:2): 0.3mg/mL; DMSO: slightly soluble; Ethanol: slightly soluble
[form ]

A crystalline solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Description]

BMS-986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor.
[Uses]

BMS-986188 is a selective positive allosteric modulator of δ-opioid receptor with an EC50 of 0.05 μM[1].
[References]

[1] Burford NT, et al. Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor. J Med Chem. 2015 May 28;58(10):4220-9. DOI:10.1021/acs.jmedchem.5b00007
Spectrum DetailBack Directory
[Spectrum Detail]

BMS 986188(1776115-10-6)1HNMR
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