| Identification | Back Directory | [Name]
Octanoic acid, 8,8'-[[2-[[2-(dimethylamino)ethyl]thio]acetyl]imino]bis-, 1,1'-di-(2Z)-2-nonen-1-yl ester | [CAS]
1777792-33-2 | [Synonyms]
Octanoic acid, 8,8'-[[2-[[2-(dimethylamino)ethyl]thio]acetyl]imino]bis-, 1,1'-di-(2Z)-2-nonen-1-yl ester | [Molecular Formula]
C40H74N2O5S | [MOL File]
1777792-33-2.mol | [Molecular Weight]
695.09 |
| Chemical Properties | Back Directory | [Boiling point ]
729.9±60.0 °C(Predicted) | [density ]
0.980±0.06 g/cm3(Predicted) | [solubility ]
DMSO:250.0(Max Conc. mg/mL);359.66(Max Conc. mM) | [form ]
Liquid | [pka]
8.89±0.28(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
ATX-001 is an ionizable lipid. It is useful for Development of Lipidoid Nanoparticles for siRNA, mRNA, and vaccine Delivery. | [Uses]
ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA[1]. | [target]
ATX inhibitor 1 is a potent ATX (IC50=1.23 nM, FS-3 and 2.18 nM, bis-pNPP) inhibitor. | [References]
[1] Arcturus Therapeutics, Inc. Preparation of ionizable cationic lipid compounds for RNA delivery. World Intellectual Property Organization, WO2015074085 A1 2015-05-21 |
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