| Identification | Back Directory | [Name]
1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- | [CAS]
1787787-60-3 | [Synonyms]
AIM2-IN-3
1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- | [Molecular Formula]
C16H14N2O2 | [MOL File]
1787787-60-3.mol | [Molecular Weight]
266.29 |
| Hazard Information | Back Directory | [Biological Activity]
NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of NLRP3 and AIM2 inflammatory bodies and has species differences. Its IC 50 value is 0.077 ± 0.008 μ M。 | [References]
[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194. |
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