| Identification | Back Directory | [Name]
endo-BCN-PEG3-acid | [CAS]
1807501-82-1 | [Synonyms]
BCN-exo-PEG3-COOH
BCN-endo-PEG3-COOH
endo-BCN-PEG3-acid
1-(Bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid | [Molecular Formula]
C20H31NO7 | [MDL Number]
MFCD31692198 | [MOL File]
1807501-82-1.mol | [Molecular Weight]
397.46 |
| Chemical Properties | Back Directory | [Boiling point ]
580.6±45.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
liquid | [pka]
4.28±0.10(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Description]
endo-BCN-PEG3-acid is a click chemistry linker consisting of a BCN group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to yield a amide bond. The BCN group can react with azide-tagged biomolecules. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
endo-BCN-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs |
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