ChemicalBook--->CAS DataBase List--->1807503-86-1

1807503-86-1

1807503-86-1 Structure

1807503-86-1 Structure
IdentificationBack Directory
[Name]

t-Boc-Aminoxy-PEG2-alcohol
[CAS]

1807503-86-1
[Synonyms]

Boc-Aminooxy-PEG2
Boc-Aminoxy-PEG2-OH
Boc-Aminooxy-PEG2-alcohol
t-Boc-Aminoxy-PEG2-alcohol
t-Boc-Aminooxy-PEG2-alcoho
t-Boc-Aminooxy-PEG2-alcohol
Carbamic acid, N-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester
[Molecular Formula]

C9H19NO5
[MDL Number]

MFCD28122959
[MOL File]

1807503-86-1.mol
[Molecular Weight]

221.25
Chemical PropertiesBack Directory
[density ]

1.108±0.06 g/cm3(Predicted)
[storage temp. ]

Storage temp. 2-8°C
[form ]

Viscous Liquid
[pka]

14.36±0.10(Predicted)
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

t-Boc-Aminooxy-PEG2-alcohol is a Boc-protected aminooxy compound. The protected aminooxy can be deprotected under mild acidic conditions and then can react with an aldehyde or ketone group to form a linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
[Uses]

Boc-Aminooxy-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

t-Boc-Aminoxy-PEG2-alcohol(1807503-86-1)1HNMR
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