| Identification | Back Directory | [Name]
t-Boc-Aminoxy-PEG2-alcohol | [CAS]
1807503-86-1 | [Synonyms]
Boc-Aminooxy-PEG2
Boc-Aminoxy-PEG2-OH
Boc-Aminooxy-PEG2-alcohol
t-Boc-Aminoxy-PEG2-alcohol
t-Boc-Aminooxy-PEG2-alcoho
t-Boc-Aminooxy-PEG2-alcohol
Carbamic acid, N-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester | [Molecular Formula]
C9H19NO5 | [MDL Number]
MFCD28122959 | [MOL File]
1807503-86-1.mol | [Molecular Weight]
221.25 |
| Chemical Properties | Back Directory | [density ]
1.108±0.06 g/cm3(Predicted) | [storage temp. ]
Storage temp. 2-8°C | [form ]
Viscous Liquid | [pka]
14.36±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
t-Boc-Aminooxy-PEG2-alcohol is a Boc-protected aminooxy compound. The protected aminooxy can be deprotected under mild acidic conditions and then can react with an aldehyde or ketone group to form a linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. | [Uses]
Boc-Aminooxy-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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