ChemicalBook--->CAS DataBase List--->1807512-46-4

1807512-46-4

Request For Quotation
1807512-46-4 Structure

1807512-46-4 Structure
IdentificationBack Directory
[Name]

Mal-PEG5-PFP
[CAS]

1807512-46-4
[Synonyms]

Mal-PEG5-PFP
4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester
[Molecular Formula]

C23H26F5NO9
[MDL Number]

MFCD26127797
[MOL File]

1807512-46-4.mol
[Molecular Weight]

555.45
Chemical PropertiesBack Directory
[Boiling point ]

594.2±50.0 °C(Predicted)
[density ]

1.376±0.06 g/cm3(Predicted)
[pka]

-2.34±0.20(Predicted)
Hazard InformationBack Directory
[Description]

Mal-PEG5-PFP is a PEG linker containing maleimide and PFP moieties. Maleimides are thiol-reactive and react between pH 6.5 and 7.5 to form thiolester bonds. PFP moieties are amine-reactive and are less susceptible to undergo hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.
[Uses]

Mal-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs; Alkyl/ether
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
1807512-46-4 suppliers list
Company Name: Hunan HuaTeng Pharmaceutical Co., Ltd.,  
Telephone: 400-8592883 15367835770
Website: www.huatengsci.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 18916372613
Website: www.shyuanye.com
Company Name: Jinan elephant international trading co., LTD  
Telephone:
Website: www.chemicalbook.com/ShowSupplierProductsList19883/0_EN.htm
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
Telephone: +86-156-80926068 +86-15680926068
Website: http://www.confluore.cn/
Company Name: SuZhou Medinoah Co.,LTD.  
Telephone: 0512-69561983 13914027025
Website: http://www.medinoah.com/
Company Name: Alpha Biopharmaceuticals Co., Ltd  
Telephone: 0411-39042497
Website: alphabiopharm.com/?reqp=1&reqr=
Company Name: Nextpeptide Inc  
Telephone: +86-0571-81612335 +8613336028439
Website: http://www.nextpeptide.com/
Company Name: Shaanxi Xinyan Bomei Biotechnology Co., Ltd.  
Telephone: 13892832556
Website: www.xinyanbm.com/
Company Name: Chongqing Chemdad Co., Ltd  
Telephone: +86-023-6139-8061 +86-86-13650506873
Website: http://www.chemdad.com/
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Telephone: 025-85563444 18351873721
Website: http://www.synzest.com
Company Name: Zhengzhou convergence chemical co., LTD  
Telephone: 037155153829 18003835034
Website: https://www.chemicalbook.com/supplier/24021783/
Company Name: Zhengzhou Akem Chemical Co., Ltd  
Telephone: 13303867194
Website: www.acmechem.cn/
Company Name: Henan Kehong Biological Technology Co. LTD  
Telephone: 0371-55969461 18638736641
Website: www.kehobio.com
Company Name: Xi'an Qiyue Biotechnology Co., Ltd.  
Telephone: 400-400-6966-012-012 17778955912
Website: http://www.qiyuebio.com/
Company Name: Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd  
Telephone: 0431-80514535 19917294565
Website: www.chemextension.com
Company Name: Aikon International Limited  
Telephone: 17714375163
Website: www.aikonchem.com
Company Name: Pushan Industry (Shaanxi) Co., Ltd.  
Telephone: 029-81310890 18165209495
Website: www.pushanshiye.com
Company Name: Shanghai Haohong Scientific Co., Ltd.  
Telephone: 400-8210725 4008210725
Website: https://www.leyan.com/
Tags:1807512-46-4 Related Product Information
1599486-33-5 1807534-78-6 2112731-42-5 357277-61-3 2229707-72-4 1421933-37-0 2353409-54-6 2575631-92-2 518044-41-2 1438853-35-0 146551-23-7 1415800-42-8 1823885-81-9 518044-40-1 1431295-77-0 2353409-52-4 2727965-49-1 1325208-25-0