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2353409-52-4

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2353409-52-4 Structure

2353409-52-4 Structure
IdentificationBack Directory
[Name]

Mal-amido-PEG8-val-gly-PAB-OH
[CAS]

2353409-52-4
[Synonyms]

Mal-amido-PEG8-val-gly-PAB-OH
[Molecular Formula]

C40H63N5O15
[MDL Number]

MFCD31811439
[MOL File]

2353409-52-4.mol
[Molecular Weight]

853.95
Chemical PropertiesBack Directory
[Boiling point ]

1051.3±65.0 °C(Predicted)
[density ]

1.231±0.06 g/cm3(Predicted)
[pka]

14.14±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Cleavable Linker
[References]

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
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