| Identification | Back Directory | [Name]
2-(t-Butoxycarbonylamido)-1,3-bis (PFP-oxycarbonylethoxy)propane | [CAS]
1807521-01-2 | [Synonyms]
C-NH-Boc-C-Bis-(C1-PEG1-PFP)
2-(t-Butoxycarbonylamido)-1,3-bis (PFP-oxycarbonylethoxy)propane
(2,3,4,5,6-Pentafluorophenyl) 3-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[3-oxo-3-(2,3,4,5,6-pentafluorophenoxy)propoxy]propoxy]propanoate | [Molecular Formula]
C26H23F10NO8 | [MDL Number]
MFCD28385477 | [MOL File]
1807521-01-2.mol | [Molecular Weight]
667.447 |
| Hazard Information | Back Directory | [Description]
2-(t-Butoxycarbonylamido)-1,3-bis(PFP-oxycarbonylethoxy)propane contains a Boc protected amino group and two PFP end groups. PFP group can react with primary amines to form a stable amide bond. | [Uses]
C-NH-Boc-C-Bis-(C1-PEG1-PFP) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|