ChemicalBook--->CAS DataBase List--->180977-44-0

180977-44-0

180977-44-0 Structure

180977-44-0 Structure
IdentificationBack Directory
[Name]

GGTI-298
[CAS]

180977-44-0
[Synonyms]

CS-2228
GGTI-298
GGTI298 (GGTI-298
GGTI298 (CF3CO2H)salt
GGTI-298 trifluoroacetate salt
N-4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-NAPHTHYLBENZOYL-(L)-LEUCINE METHYL ESTER, TFA
L-Leucine, N-[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
N-[[4-(2-(R)-AMINO-3-MERCAPTOPROPYL)AMINO]-2-NAPHTHYLBENZOYL]LEUCINE METHYL ESTER TRIFLUOROACETATE SALT
N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt
N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-(1-naphthalenyl)benzoyl]-L-leucinemethylestertrifluoroacetatesalt
methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate,2,2,2-trifluoroacetic acid
[EINECS(EC#)]

604-604-1
[Molecular Formula]

C27H33N3O3S
[MDL Number]

MFCD06409252
[MOL File]

180977-44-0.mol
[Molecular Weight]

479.63
Chemical PropertiesBack Directory
[Melting point ]

99.5-100 °C
[storage temp. ]

−20°C
[solubility ]

DMSO: 22 mg/mL
[form ]

solid
[color ]

off-white
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

GGTI 298 is a CAAX peptidomimetic that selectively inhibits geranylgeranyltransferase I (GGTase I). It has been shown to arrest human tumor cells and induce apoptosis.
[Definition]

ChEBI: (2S)-2-[[[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)phenyl]-oxomethyl]amino]-4-methylpentanoic acid methyl ester is a leucine derivative.
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