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181427-66-7

181427-66-7 Structure

181427-66-7 Structure
IdentificationBack Directory
[Name]

β-Amyloid (10-35), amide
[CAS]

181427-66-7
[Synonyms]

β-Amyloid (10-35)
β-Amyloid (10-35), amide
[Molecular Formula]

C133H205N35O36S
[MDL Number]

MFCD07366682
[MOL File]

181427-66-7.mol
[Molecular Weight]

2902.37
Chemical PropertiesBack Directory
[Boiling point ]

2714.6±65.0 °C(Predicted)
[density ]

1.294±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[Sequence]

Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-NH2
Hazard InformationBack Directory
[Uses]

β-Amyloid (10-35), amide is composed of 26 aa (10-35 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer’s disease.
[References]

[1] Benzinger TL, et al. Propagating structure of Alzheimer's beta-amyloid(10-35) is parallel beta-sheet with residues in exact register. Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13407-12. DOI:10.1073/pnas.95.23.13407
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