| Identification | Back Directory | [Name]
2,4,6,8,10,14,20,22,24,26,28,40,50,54-Dohexacontatetradecaenoic acid, 62-amino-17,19,31,35,37,39,43,45,47,49,53,57,59-tridecahydroxy-2,16,18,32-tetramethyl-33-oxo-, (2E,4E,8E,10E,14E,20E,26E,28E,40E,50E,54E)- | [CAS]
182291-65-2 | [Synonyms]
Linearmycin B
2,4,6,8,10,14,20,22,24,26,28,40,50,54-Dohexacontatetradecaenoic acid, 62-amino-17,19,31,35,37,39,43,45,47,49,53,57,59-tridecahydroxy-2,16,18,32-tetramethyl-33-oxo-, (2E,4E,8E,10E,14E,20E,26E,28E,40E,50E,54E)- | [Molecular Formula]
C66H103NO16 | [MOL File]
182291-65-2.mol | [Molecular Weight]
1166.52 |
| Chemical Properties | Back Directory | [Boiling point ]
1249.0±65.0 °C(Predicted) | [density ]
1.169±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: Soluble
Methanol: Soluble | [form ]
A solid | [pka]
4.65±0.19(Predicted) |
| Hazard Information | Back Directory | [Uses]
Linearmycin B is an antibacterial and antifungal agent. Linearmycin B shows activity against Bacillus subtilis (Bs), Staphylococcus aureus (Sa). Candida albicans (Ca), and Saccharomyces cerevisiae (Sc), with MIC values of 0.097, 1.5, 0.0008, and 0.0002 μg/mL, respectively[1]. | [Biological Activity]
Linearmycin B is a polyene antibiotic that has been found in Streptomyces.1 It induces lysis and degradation of B. subtilis as a component of Streptomyces Mg1 extract.2 | [References]
1.Sakuda, S., Guce-Bigol, U., Itoh, M., et al.Novel linear polyene antibiotics: LinearmycinsJ. Chem. Soc., Perkin Trans. 1182315-2319(1996)
2.Stubbendieck, R.M., and Straight, P.D.Escape from lethal bacterial competition through coupled activation of antibiotic resistance and a mobilized subpopulationPLoS Genet.11(12)e1005722(2015)
|
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
ChemeGen
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
|