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182415-09-4

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182415-09-4 Structure

182415-09-4 Structure
IdentificationBack Directory
[Name]

Piclozotan
[CAS]

182415-09-4
[Synonyms]

SUN4057
SUN-4057
SUNN4057
SUNN-4057
Piclozotan
SUN-N-4057
Piclozotan (anhydrous)
5-Hydroxy Saxagliptin Hydrochloride
1,4-Benzoxazepin-5(4H)-one, 3-chloro-4-[4-(3',6'-dihydro[2,4'-bipyridin]-1'(2'H)-yl)butyl]-
[Molecular Formula]

C23H24ClN3O2
[MDL Number]

MFCD00950987
[MOL File]

182415-09-4.mol
[Molecular Weight]

409.91
Chemical PropertiesBack Directory
[solubility ]

DMSO: soluble
Hazard InformationBack Directory
[Uses]

Piclozotan (SUN N4057) is a 5HT1A receptor agonist. Piclozotan improves motor complications in Parkinson's disease model[1].
[IC 50]

5-HT1A Receptor
[References]

[1] Tani Y, et al. Effects of piclozotan (SUN N4057), a partial serotonin 1A receptor agonist, on motor complications induced by repeated administration of levodopa in parkinsonian rats. Eur J Pharmacol. 2010 Dec 15;649(1-3):218-23. DOI:10.1016/j.ejphar.2010.09.013
Spectrum DetailBack Directory
[Spectrum Detail]

Piclozotan(182415-09-4)1HNMR
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