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182422-45-3

182422-45-3 Structure

182422-45-3 Structure
IdentificationBack Directory
[Name]

Cyclo(L-asparaginyl-L-α-aspartyl-L-tryptophyl-L-valyl-L-ornithyl-L-leucyl-D-tyrosyl-L-prolyl-L-phenylalanyl-D-phenylalanyl)
[CAS]

182422-45-3
[Synonyms]

Loloatin B 10
Cyclo(L-asparaginyl-L-α-aspartyl-L-tryptophyl-L-valyl-L-ornithyl-L-leucyl-D-tyrosyl-L-prolyl-L-phenylalanyl-D-phenylalanyl)
[Molecular Formula]

C67H85N13O14
[MOL File]

182422-45-3.mol
[Molecular Weight]

1296.47
Chemical PropertiesBack Directory
[Melting point ]

220-226 °C
[Boiling point ]

1670.4±65.0 °C(Predicted)
[density ]

1.37±0.1 g/cm3(Predicted)
[pka]

4.00±0.10(Predicted)
[Sequence]

Cyclo(Asn-Asp-Trp-Val-{Orn}-Leu-{D-Tyr}-Pro-Phe-{D-Phe})
Hazard InformationBack Directory
[Uses]

Loloatin B 10 is an antibiotic, which exhibits antibacterial efficacy against gram positive antibiotic resistant human pathogens[1].
[References]

[1] Gerard JM, et al., Loloatins A-D, cyclic decapeptide antibiotics produced in culture by a tropical marine bacterium. J Nat Prod. 1999 Jan;62(1):80-5. DOI:10.1021/np980219f
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