| Identification | Back Directory | [Name]
Benzonitrile, 2-chloro-4-[5,8-dihydro-4-[[5-(1-hydroxy-1-methylethyl)-2-pyridinyl]amino]pyrido[3,4-d]pyrimidin-7(6H)-yl]- | [CAS]
1831085-48-3 | [Synonyms]
Gumelutamide
Benzonitrile, 2-chloro-4-[5,8-dihydro-4-[[5-(1-hydroxy-1-methylethyl)-2-pyridinyl]amino]pyrido[3,4-d]pyrimidin-7(6H)-yl]- | [Molecular Formula]
C22H21ClN6O | [MOL File]
1831085-48-3.mol | [Molecular Weight]
420.89 |
| Chemical Properties | Back Directory | [Boiling point ]
671.9±55.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.72±0.29(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Gumelutamide is a tetrahydropyridopyrimidine compound, acting as an antiandrogen, antineoplastic agent. Gumelutamide is an androgen antagonist[1][2]. | [References]
[1] Kazuhisa M, et al. Preparation of novel tetrahydropyridopyrimidine compounds, and antiandrogens and antitumor agents containing them: World Intellectual Property Organization, WO2015182712. 2015-12-03.
[2] WHO Drug Information-World Health Organization (WHO). |
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