| Identification | More | [Name]
4-METHYLUMBELLIFERYL OLEATE | [CAS]
18323-58-5 | [Synonyms]
4-MU-OLEATE
Einecs 242-210-7
4-METHYLUMBELLIFERYL OLEATE
4-Methylumbelliferone oleate
Oleoyl 4-MethyluMbelliferone
4-MethylumbelliferylOleateA.R.
7-Hydroxy-4-MethylcouMarin Oleate
4-methylumbrellaketoneoleate，4-MUO
4-Methyl-2-oxo-2H-chroMen-7-yl oleate
OLEIC ACID-4-METHYLUMBELLIFERYL ESTER
4-methyl-2-oxo-2H-1-benzopyran-7-yl oleate
4-METHYLUMBELLIFERYL OLEATE, FOR FLUORES CENCE
(4-Methyl-2-oxochromen-7-yl) (Z)-octadec-9-enoate
4-Methylumbelliferyl oleate, suitable for fluorescence, ≥95%
(9Z)-octadec-9-enoic acid 4-methyl-2-oxo-2H-chromen-7-yl ester
(Z)-9-Octadecenoic acid 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
(9Z)-9-Octadecenoic Acid 4-Methyl-2-oxo-2H-1-benzopyran-7-yl Ester
(Z)-9-Octadecenoic acid (4-methyl-2-oxo-2H-1-benzopyran-7-yl) ester
9-Octadecenoic acid (Z)-, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
9-Octadecenoic acid (9Z)-, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester | [EINECS(EC#)]
242-210-7 | [Molecular Formula]
C28H40O4 | [MDL Number]
MFCD00076095 | [Molecular Weight]
440.61 | [MOL File]
18323-58-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Colourless Oil | [Melting point ]
37-38 °C (lit.) | [Boiling point ]
471.81°C (rough estimate) | [density ]
1.023 | [refractive index ]
1.4840 (estimate) | [Fp ]
281.3℃ | [storage temp. ]
−20°C
| [solubility ]
2-methoxyethanol: soluble | [form ]
Solid | [color ]
Colorless to Pale Yellow Oil | [BRN ]
4887028 | [InChI]
1S/C28H40O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(29)31-24-19-20-25-23(2)21-28(30)32-26(25)22-24/h10-11,19-22H,3-9,12-18H2,1-2H3/b11-10- | [InChIKey]
NKQFKJYKCVDLPT-KHPPLWFESA-N | [SMILES]
CCCCCCCC\C=C/CCCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1 | [CAS DataBase Reference]
18323-58-5(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases.1,2,3 It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.4 | [Chemical Properties]
Colourless Oil | [Uses]
4-Methylumbelliferyl oleate has been used:
- as a substrate to assay the activity of non-specific esterases
- to determine lipase activity
- as a substrate to evaluate pancreatic lipase inhibitory activity
| [Uses]
4-Methylumbelliferyl oleate can act as Fatty acyl esters for use as fluorogenic substrates to continuously follow the hydrolytic activity of carboxylesterases, such as acid and alkaline lipases.
| [Uses]
Fluorogenic substrate for lipases. | [References]
[1] M L ARMSTRONG. Lipid metabolism in xanthomatous skin of hypercholesterolemic rabbits.[J]. American Journal of Pathology, 1986, 125 2: 339-348.
[2] BERNARD J MONCLA K M P. Oleate lipase activity in Gardnerella vaginalis and reconsideration of existing biotype schemes.[J]. ACS Applied Energy Materials, 2009: 78. DOI: 10.1186/1471-2180-9-78
[3] AKIHIRO OGAWA. Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects.[J]. Lipids in Health and Disease, 2015, 14: 20. DOI: 10.1186/s12944-015-0019-0 | [Excitation / Emission Maximum]
330 nm (pH 4.6), 370 nm (pH 7.4), 385 nm (pH 10.4)/445-454 nm |
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