| Identification | Back Directory | [Name]
3-((Dimethylamino)propyl)triphenylphosphonium bromide | [CAS]
18355-96-9 | [Synonyms]
Olopatadine int
(3-(Dimethylamino)
Olopatadine Impurity 19
3-(dimethylamino)propyl-triphenylphosphanium
(3-Dimethylamino)propyltriphenylphosphonium bromide
(3-BROMIDEPROPYL)TRIPHENYLPHOS-PHONIUM BROMIDE, 98+%
(3-(Dimethylamino)propyl)triphenylphosphonium bromide 98%
(3-(DiMethylaMino)propyl)triphenylphosphoniuM broMide
3-(DIMETHYLAMINO)PROPYL]TRIPHENYLPHOSPHONIUM BROMIDE [WITTING REAGENT
(3-(DiMethylaMino)propyl)triphenylphosphoniuM broMide(3-(DiMethylaMino)propyl)triphenylphosphoniuM broMide | [EINECS(EC#)]
605-998-7 | [Molecular Formula]
C23H27BrNP | [MDL Number]
MFCD00012200 | [MOL File]
18355-96-9.mol | [Molecular Weight]
428.35 |
| Chemical Properties | Back Directory | [Melting point ]
193-196 °C | [storage temp. ]
Inert atmosphere,Room Temperature | [Appearance]
White to off-white Solid | [BRN ]
4637548 | [InChI]
InChI=1S/C23H27NP.BrH/c1-24(2)19-12-20-25(21-13-6-3-7-14-21,22-15-8-4-9-16-22)23-17-10-5-11-18-23;/h3-11,13-18H,12,19-20H2,1-2H3;1H/q+1;/p-1 | [InChIKey]
SSWPSKSQQSJKKF-UHFFFAOYSA-M | [SMILES]
[P+](C1C=CC=CC=1)(C1C=CC=CC=1)(C1C=CC=CC=1)CCCN(C)C.[Br-] |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
(3-(Dimethylamino)propyl)triphenyl-phosphonium Bromide is used in preparation of olopatadine hydrochloride. | [Uses]
Reactant for preparation of:
- Topoisomerase I-targeting antitumor agents
- C15-C21 stereopentad of discodermolide via cleavage of aminoglycosides, double-bond isomerization, and selective hydroxyl group protection
- Diphenyl amine based sodium channel blockers, effective against hNav1.2
- Reactant for Wittig reaction with benzaldehyde
| [reaction suitability]
reaction type: C-C Bond Formation |
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