| Identification | Back Directory | [Name]
N-[3-(1H-IMIDAZOL-4-YL)PROPYL]-1H-BENZIMIDAZOL-2-AMINE DIOXALATE | [CAS]
184576-87-2 | [Synonyms]
ROS 234 DIOXALATE
1H-Benzimidazol-2-amine, N-[3-(1H-imidazol-5-yl)propyl]-
N-[3-(1H-IMIDAZOL-4-YL)PROPYL]-1H-BENZIMIDAZOL-2-AMINE DIOXALATE | [Molecular Formula]
C13H15N5 | [MDL Number]
MFCD09998818 | [MOL File]
184576-87-2.mol | [Molecular Weight]
241.29 |
| Chemical Properties | Back Directory | [Boiling point ]
558.4±52.0 °C(Predicted) | [density ]
1.341±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
Soluble to 50 mM in water and to 50 mM in DMSO | [form ]
Powder | [pka]
11.47±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
ROS 234 Dioxalate is a potent histamine H3 receptor antagonist. | [Biological Activity]
Potent H 3 antagonist (pK B at guinea-pig ileum H 3 -receptor = 9.46). Limited blood brain barrier permeability (ED 50 = 19.12 mg/kg i.p.). | [in vivo]
ROS 234 centrally injected, significantly shortens pentobarbital narcosis[1]. | [IC 50]
rat H3 receptor: 8.90 (pKi) | [storage]
Desiccate at RT |
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BOC Sciences
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https://www.bocsci.com |
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