| Identification | More | [Name]
2-(METHYLTHIO)ETHYLAMINE | [CAS]
18542-42-2 | [Synonyms]
1-AMINO-3-THIABUTANE
2-AMINOETHYL METHYL SULFIDE
2-(METHYLMERCAPTO)ETHYLAMINE
2-(METHYLTHIO)ETHYLAMINE
RARECHEM AL BW 0219
S-METHYLCYSTEAMINE
1-Amino-2-(methylthio)ethane
1-Aza-4-thiapentane
2-(Methylthio)ethanamine
2-Aminoethylmethylsulphide
2-Methylsulfanyl-ethylamine
Ethanamine,2-(methylthio)-
Ethylamine,2-(methylthio)-
2-Aminoethyl methyl sulphide~5-Methylcysteamine
5-methylcysteamine
2-(Methylthio)ethylamine, 95+%
Aminoethyl methyl sulphide 95+%
2-Aminoethyl methyl sulfide, S-Methylcysteamine
Methyl 2-aminoethyl sulfide | [EINECS(EC#)]
242-412-5 | [Molecular Formula]
C3H9NS | [MDL Number]
MFCD00014825 | [Molecular Weight]
91.18 | [MOL File]
18542-42-2.mol |
| Questions And Answer | Back Directory | [Synthesis]
Reports on the synthesis of thioetheramines are scarce. Literature reports the synthesis of thioetheramines by reacting ethyl bromide with metallic sodium in an ethanol solvent with hexamethylene mercaptan. However, the distillation temperature during separation and purification is as high as 200-220℃, the reaction is vigorous, difficult to control, and costly. The synthetic principle is as follows: ethyl bromide hydrochloride reacts with triethylamine in a hexanol solvent to produce chloroethylamine. Hexamethylene mercaptan reacts with sodium hydride in an ethylene glycol diethyl ether solvent to obtain sodium hexamethylene mercaptan. Sodium hexamethylene mercaptan reacts with 2-chloroethylamine to synthesize thioetheramines, with disulfides as the main byproduct. This paper uses ethylene glycol diethyl ether as a solvent and iodomethane, sodium hydride, and aminoethanethiol as raw materials to synthesize thioetheramines. The reaction conditions are mild, the process is simple, easy to operate, and the cost is low. The synthetic reaction formula for 2-(METHYLTHIO)ETHYLAMINE is shown in the figure below: 
Figure 1 Synthetic reaction formula for 2-(METHYLTHIO)ETHYLAMINE |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless liquid | [Boiling point ]
146-149 °C(lit.) | [density ]
0.98 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.495(lit.)
| [Fp ]
119 °F
| [storage temp. ]
Flammables area | [form ]
Crystalline Powder | [pka]
pK1:9.18(+1) (30°C) | [color ]
Off-white to light brown | [Specific Gravity]
0.974 | [Water Solubility ]
Soluble in water. | [Sensitive ]
Air Sensitive | [BRN ]
1731099 | [InChI]
1S/C3H9NS/c1-5-3-2-4/h2-4H2,1H3 | [InChIKey]
CYWGSFFHHMQKET-UHFFFAOYSA-N | [SMILES]
CSCCN | [CAS DataBase Reference]
18542-42-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C,F,Xi | [Risk Statements ]
R10:Flammable.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2734 8/PG 2
| [WGK Germany ]
3
| [F ]
10-13-23 | [Hazard Note ]
Corrosive/Highly Flammable | [TSCA ]
T | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29309090 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Flam. Liq. 3
Skin Corr. 1B |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 18918157536; |
| Website: |
http://www.energy-chemical.com |
|