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18585-06-3

18585-06-3 Structure

18585-06-3 Structure
IdentificationBack Directory
[Name]

ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE
[CAS]

18585-06-3
[Synonyms]

RG-S3-YZ
TIMTEC-BB SBB008265
Regorafenib Impurity 39
Sorafenib related coMpound 2
Regorafenib Ethyl Carbamate Impurity
ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE
Ethyl 4-chloro-3-(trifluoromethyl)phenylcarbamate
ethyl N-[4-chloro-3-(trifluoromethyl)phenyl]carbamate
N-[4-chloro-3-(trifluoromethyl)phenyl]carbamic acid ethyl ester
Carbamic acid, N-[4-chloro-3-(trifluoromethyl)phenyl]-, ethyl ester
Sorafenib impurity 1/ethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate
Regorafenib Ethyl Carbamate ImpurityQ: What is Regorafenib Ethyl Carbamate Impurity Q: What is the CAS Number of Regorafenib Ethyl Carbamate Impurity Q: What is the storage condition of Regorafenib Ethyl Carbamate Impurity Q: What are the applications of Regorafenib Ethyl Carbamate Impurity
[Molecular Formula]

C10H9ClF3NO2
[MDL Number]

MFCD00043450
[MOL File]

18585-06-3.mol
[Molecular Weight]

267.63
Chemical PropertiesBack Directory
[Boiling point ]

252.5±40.0 °C(Predicted)
[density ]

1.402±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

12.44±0.70(Predicted)
[color ]

White to Off-White
[InChI]

1S/C10H9ClF3NO2/c1-2-17-9(16)15-6-3-4-8(11)7(5-6)10(12,13)14/h3-5H,2H2,1H3,(H,15,16)
[InChIKey]

BAFPGGUKCVCSKG-UHFFFAOYSA-N
[SMILES]

FC(F)(F)c1c(ccc(c1)NC(=O)OCC)Cl
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Ethyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.
Spectrum DetailBack Directory
[Spectrum Detail]

ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE(18585-06-3)1HNMR
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