ChemicalBook--->CAS DataBase List--->1256817-30-7

1256817-30-7

1256817-30-7 Structure

1256817-30-7 Structure
IdentificationBack Directory
[Name]

Sorafenib IMpurity
[CAS]

1256817-30-7
[Synonyms]

Sorafenib Impurity
Sorafenib Impurity 24
Sorafenib Related Compound 16
Methyl 4-(Methylamino)picolinate
methyl 4-(methylamino)pyridine-2-carboxylate
Sorafenib impurity 7/Methyl 4-(Methylamino)picolinate
methyl 4-(methylamino)picolinate? (Sorafenib Impurity)
2-Pyridinecarboxylic acid, 4-(methylamino)-, methyl ester
4-(4-(3-(2-chloro-3-(trifluoroMethyl)phenyl)ureido)phenoxy)-N-MethylpicolinaMide
[Molecular Formula]

C21H16ClF3N4O3
[MOL File]

1256817-30-7.mol
[Molecular Weight]

464.825
Chemical PropertiesBack Directory
[Boiling point ]

326.9±27.0 °C(Predicted)
[density ]

1.186±0.06 g/cm3(Predicted)
[pka]

4.84±0.10(Predicted)
[CAS DataBase Reference]

1256817-30-7
Hazard InformationBack Directory
[Uses]

Methyl 4-(Methylamino)picolinate is a pyridinyl building block and a useful synthetic intermediate.
[Synthesis]

Add 0.8 g (0.004 mol) of 2-chloro-3-trifluoromethyl aniline and 0.7 g (0.004 mol) of N,N-carbonyl diimidazole to 10 mL of dichloromethane, stirring at room temperature for 4 h. Add 0.6 g (0.002 mol) of Compound 2, stirring for 6 h. Distil under reduced pr
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