| Identification | Back Directory | [Name]
MAB-CHMINACA | [CAS]
1863065-92-2 | [Synonyms]
MAB-CHMINACA
MAB-CHMINACA (CRM)
MAB-CHMINACA SOLUTION
ZWCCSIUBHCZKOY-UHFFFAOYSA-N
N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)indazole-3-carboxamide
N-[1-(Aminocarbonyl)-2,2-dimethylpropyl]-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide
1H-Indazole-3-carboxamide, N-[1-(aminocarbonyl)-2,2-dimethylpropyl]-1-(cyclohexylmethyl)- | [Molecular Formula]
C21H30N4O2 | [MOL File]
1863065-92-2.mol | [Molecular Weight]
370.49 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml | [form ]
A neat solid |
| Hazard Information | Back Directory | [Description]
AB-CHMINACA is an indazole-based synthetic cannabinoid (CB) that is structurally related to AB-FUBINACA (Item Nos. ISO60211 | ISO00134 | 14039), a high affinity ligand of the CB1 receptor (Ki = 0.9 nM). MAB-CHMINACA is structurally similar to AB-CHMINACA by bearing an identical cyclohexyl group; however, the isobutyl moiety is substituted with a tert-butyl group. It is a potent agonist of the CB1 receptor with a reported Ki value of 0.289 nM. This product is intended for forensic and research applications. | [Uses]
N-[1-(Aminocarbonyl)-2,2-dimethylpropyl]-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide is an impurity of MAB-CHMINACA (A105960) and 5-fluoro-ADB-PINACA, an indazole-based synthetic cannabinoid that is structurally related to AB-FUBINACA, a high affinity ligand of the central CB1 receptor. it is also used in the studies on the identification and quantitation of 5-fluoro-ADB-PINACA and MAB-CHMINACA indazole-based cannabinoids in dubious herbal products. Synthetic cannabinoids. | [References]
[1] CARLIER J, DIAO X, SEMPIO C, et al. Identification of New Synthetic Cannabinoid ADB-CHMINACA (MAB-CHMINACA) Metabolites in Human Hepatocytes[J]. The AAPS Journal, 2017, 71 2 1: 0. DOI: 10.1208/s12248-016-0037-5
[2] KOUTARO HASEGAWA. Postmortem distribution of MAB-CHMINACA in body fluids and solid tissues of a human cadaver.[J]. Forensic Toxicology, 2015, 33 2: 380-387. DOI: 10.1007/s11419-015-0272-y
[3] PIOTR ADAMOWICZ Joanna G. Acute intoxication of four individuals following use of the synthetic cannabinoid MAB-CHMINACA.[J]. Clinical toxicology (Philadelphia, Pa.), 2016: 650-654. DOI: 10.1080/15563650.2016.1190016 |
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