| Identification | Back Directory | [Name]
H-TRP-LYS-TYR-MET-VAL-MET-NH2 | [CAS]
187986-11-4 | [Synonyms]
WKYMVM-NH2
WKYMVMAMIDE
W Peptide, WKYMVm
TRP-LYS-TYR-MET-VAL-MET-NH2
WKYMVM trifluoroacetate salt
H-TRP-LYS-TYR-MET-VAL-MET-NH2
Trp-Lys-Tyr-Met-Val-L-Met NH2 trifluoroacetate salt
L-tryptophyl-L-lysyl-L-tyrosyl-L-methionyl-L-valyl-L-methioninamide | [Molecular Formula]
C41H61N9O7S2 | [MDL Number]
MFCD03093686 | [MOL File]
187986-11-4.mol | [Molecular Weight]
856.11 |
| Chemical Properties | Back Directory | [Boiling point ]
1269.6±65.0 °C(Predicted) | [density ]
1.268±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [solubility ]
H2O: >2mg/mL | [form ]
powder | [pka]
9.82±0.15(Predicted) | [color ]
white to off-white | [Water Solubility ]
H2O: >2mg/mL |
| Hazard Information | Back Directory | [Uses]
WKYMVM trifluoroacetate salt was used as a test compound for investigating the mechanism of regulation of lipoprotein-associated phospholipase A2 (Lp-PLA2). | [Biological Activity]
WKYMVM is a peptide agonist of formyl peptide receptors. WKYMVM binds to and stimulates FPRL family members 12 with EC50 values of 2 and 80 nMrespectively. The peptide is a potent activator of neutrophils.''WKYMVM is an agonist and potent activator of Formyl peptide receptor like-1 (FPRL1). WKYMVM stimulates FPRL1 and hence attenuates the function of the chemokine receptors CCR5 and CXCR4. WKYMVM activates human eosinophils to induce superoxide production through Phosphoinositide 3-Kinase-Mediated ERK1/2 pathway. | [storage]
-20°C, protect from light |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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