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188352-45-6

188352-45-6 Structure

188352-45-6 Structure
IdentificationBack Directory
[Name]

Pyridine, 4-[2-(4-fluorophenyl)-5-[4-(methylsulfinyl)phenyl]-1H-pyrrol-3-yl]-
[CAS]

188352-45-6
[Synonyms]

L167307
L-167307
L 167307
L 167307,L167307
Pyridine, 4-[2-(4-fluorophenyl)-5-[4-(methylsulfinyl)phenyl]-1H-pyrrol-3-yl]-
[Molecular Formula]

C22H17FN2OS
[MOL File]

188352-45-6.mol
[Molecular Weight]

376.45
Chemical PropertiesBack Directory
[Boiling point ]

567.4±50.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[pka]

14.86±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

L-167307 is an effective pyrrole-based p38 kinase inhibitor that can reduce secondary paw swelling in rat adjuvant-induced arthritis models[1].
[References]

[1] de Laszlo SE, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2689-94. DOI:10.1016/s0960-894x(98)00495-8
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