| Identification | Back Directory | [Name]
L-ALPHA-LYSOPHOSPHATIDYLCHOLINE | [CAS]
9008-30-4 | [Synonyms]
SOY PC
EGG PC
EGG LYSO PC
fromeggyolk
SOY LYSO PC
LYSOLECITHIN
L-α-Lysolecithin
LPC?(egg)?(neat)
SOY TOTAL EXTRACT
LYSOLECITHIN, EGG
L-A-LECITHIN (PLANT)
L-ALPHA-LYSOLECITHIN
L-A-PHOSPHATIDYLCHOLINE
LYSO-PHOSPHATIDYLCHOLINE
Lysophosphatidylcholines
L-ALPHA-LYSOLECITHIN TYPE I
L-ALPHA-LYSOLECITHIN TYPE V
L-α-Lysophosphatidylcholine
3-SN-LYSOPHOSPHATIDYLCHOLINE
Lysophosphatidylcholine (Soy)
TOTAL EGG PHOSPHATIDE EXTRACT
L-ALPHA-LYSOLECITHIN TYPE III
LPC?(liver,?bovine?or?porcine)
L-ALPHA-LYSO-LECITHIN, EGG YOLK
L-ALPHA-LYSOPHOSPHATIDYLCHOLINE
L-A-LYSOPHOSPHATIDYLCHOLINE (EGG)
1-acyl-sn-glycero-3-phosphocholine
L-A-LYSOPHOSPHATIDYLCHOLINE (PLANT)
L-A-LYSOPHOSPHATIDYLCHOLINE TYPE I*F
L-A-LYSOPHOSPHATIDYLCHOLINE*FROM SOY
Lysophosphatidylcholine from egg yolk
Lysophosphatidylcholine from soya bean
L-ALPHA-LYSOPHOSPHATIDYLCHOLINE TYPE I
L-ALPHA-LYSOPHOSPHATIDYLCHOLINE TYPE V
L-ALPHA-LYSOPHOSPHATIDYLCHOLINE TYPE III
l-a-lysophosphatidylcholine*fromsoybeans
l-α-lysophosphatidylcholine from egg yolk
L-α-lysophosphatidylcholine, from Egg Yolk
L-á-Lysophosphatidylcholine (from egg yolk)
L-á-Lysophosphatidylcholine (from soyabean)
l-α-lysophosphatidylcholine from bovine brain
l-α-lysophosphatidylcholine from bovine liver
L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, FROM EGG YOLK
L-á-Lysophosphatidylcholine (from bovine brain)
3-sn-Lysophosphatidylcholine, L-α-Lysolecithin
L-A-LYSOPHOSPHATIDYLCHOLINE TYPE I*FROM EGG YOLK
L-A-LYSOPHOSPHATIDYLCHOLINE TYPE V*FROM BOVINE BRAI
L-A-LYSOPHOSPHATIDYLCHOLINE TYPE III*FRO M BOVINE LI
l-α-lysophosphatidylcholine from glycine max (soybean)
L-α-Lysophosphatidylcholine, from egg yolk ≥99% Type I
L-alpha-Lysophosphatidylcholine from Glycine max (soybean)
L-α-Lysophosphatidylcholine from egg yolk ~99%, Type I, powder
Lysophosphatidylcholine (350 mg) (INTERNATIONAL COLD CHAIN SHIPMENT REQUIRED)
L-α-Lysophosphatidylcholine from egg yolk,1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin
L-α-Lysophosphatidylcholine from Glycine max (soybean),1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin | [EINECS(EC#)]
232-715-0 | [Molecular Formula]
NULL | [MDL Number]
MFCD00131444 |
| Chemical Properties | Back Directory | [density ]
1.47 g/mL at 20 °C(lit.) | [storage temp. ]
-20°C | [solubility ]
chloroform/methanol (9:1): 50 mg/mL, clear, colorless | [form ]
powder | [color ]
white | [biological source]
soybean |
| Hazard Information | Back Directory | [Uses]
L-alpha-Lysophosphatidylcholine (from egg yolk) is a major component of oxidized low density lipoproteins that has been implicated in various inflammatory reactions. | [Uses]
L-α-Lysophosphatidylcholine from egg yolk has been used:
- as a surfactant
- as a media supplement and in Staphylococcus aureus inhibition assay in dermatitis
- as a demyelinating agent for nerve
- as a component in sperm nuclei preparation buffer
| [Definition]
ChEBI: 1-acetyl-sn-glycero-3-phosphocholine is a 1-O-acyl-sn-glycero-3-phosphocholine. | [General Description]
L-α-Lysophosphatidylcholine is a major plasma lipid, derived from phosphatidylcholines that includes glycerol and sphingoid based lipids with one fatty acid. It is an important cell signaling molecule for G-protein coupled receptors. | [Biochem/physiol Actions]
L-α-Lysophosphatidylcholine possess cytotoxic effects and is present at high level in ischemia and atherosclerotic aortas. | [in vivo]
Lysophosphatidylcholines (0.1-20 mg/kg, Oral, single dose) protects against sepsis-induced lethality on albino ICR mice[4].
Lysophosphatidylcholines (0.1-20 mg/kg, Oral, single dose) enhances bacterial clearance, blocks cecal ligation and puncture (CLP)-induced neutrophil deactivation and increases bactericidal activity of neutrophils[4]. | Animal Model: | Albino ICR mice [4] | | Dosage: | 0.1 mg/kg, 1 mg/kg, 10 mg/kg, 20 mg/kg | | Administration: | Oral | | Result: | Provided significant protection against cecal ligation and puncture (CLP)-induced lethality at a dose of 1 mg/kg. |
| [IC 50]
IL-1β; ERK1; ERK2 | [storage]
Store at -20°C |
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