| Identification | Back Directory | [Name]
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE | [CAS]
189224-48-4 | [Synonyms]
KU14R
CS-891
KU-14R; KU 14R
2-(2-ethyl-3H-1-benzofuran-2-yl)-1H-imidazole
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE
1H-IMidazole,2-(2-ethyl-2,3-dihydro-2-benzofuranyl)-
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE USP/EP/BP | [Molecular Formula]
C13H14N2O | [MDL Number]
MFCD01861185 | [MOL File]
189224-48-4.mol | [Molecular Weight]
214.26 |
| Chemical Properties | Back Directory | [Boiling point ]
428.1±34.0 °C(Predicted) | [density ]
1.181±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Powder | [pka]
13.14±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
KU14R is a putative imidazoline I3 receptor antagonist, which blocks the effects of the atypical I3 agonist efaroxan. | [Definition]
ChEBI: 2-(2-ethyl-3H-benzofuran-2-yl)-1H-imidazole is a member of 1-benzofurans. | [Biological Activity]
Antagonist of the atypical imidazoline binding site (putative I 3 receptor) of pancreatic β -cells. Selectively blocks efaroxan-induced insulin secretion in vitro and in vivo . | [storage]
Store at -20°C |
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