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189450-19-9

189450-19-9 Structure

189450-19-9 Structure
IdentificationBack Directory
[Name]

CORTISTATIN-17 (HUMAN)
[CAS]

189450-19-9
[Synonyms]

CORTISTATIN-17 (HUMAN)
M.W. 2151.53 C96H139N27O24S3
Cortistatin-17 (human) (H-5536.0500)
Cortistatin-17 (human) trifluoroacetate salt
ASP-ARG-MET-PRO-CYS-ARG-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS
H-ASP-ARG-MET-PRO-CYS-ARG-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS-OH
H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH, (Disulfide bond)
ASP-ARG-MET-PRO-CYS-ARG-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS (DISULFIDE BRIDGE CYS5-CYS16)
Cortistatin-17 (human) trifluoroacetate salt H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH trifluoroacetate salt (Disulfide bond)
[Molecular Formula]

C96H141N27O24S3
[MDL Number]

MFCD25372009
[MOL File]

189450-19-9.mol
[Molecular Weight]

2153.51
Chemical PropertiesBack Directory
[density ]

1.52±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[form ]

Solid
[color ]

White to off-white
[Sequence]

Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge: Cys5-Cys16)
Hazard InformationBack Directory
[Uses]

Cortistatin-17 (human) is a somatostatin neuropeptide with potential for studying diseases such as cancer, inflammation, autoimmunity, fibrosis, and pain[1][2].
[References]

[1] Spier AD, et al. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res Brain Res Rev. 2000 Sep;33(2-3):228-41. DOI:10.1016/s0165-0173(00)00031-x
[2] Campos-Salinas J, et al. Therapeutic Effect of a Latent Form of Cortistatin in Experimental Inflammatory and Fibrotic Disorders. Pharmaceutics. 2022 Dec 13;14(12):2785. DOI:10.3390/pharmaceutics14122785
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