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189498-57-5

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189498-57-5 Structure

189498-57-5 Structure
IdentificationBack Directory
[Name]

ABT 080
[CAS]

189498-57-5
[Synonyms]

ABT 080
VML-530
ABT-080 (VML-530
[Molecular Formula]

C37H33N2NaO4
[MDL Number]

MFCD00953520
[MOL File]

189498-57-5.mol
[Molecular Weight]

592.67
Hazard InformationBack Directory
[Uses]

ABT-080 is an orally active inhibitor of leukotriene biosynthesis. ABT-080 simultaneously blocks the leukotriene pathways leading to the synthesis of LTB4 and LTC4, but does not inhibit PGH2 biosynthesis. ABT-080 can block bronchoconstriction and be used in the research of asthma and related inflammations[1]
[References]

[1] Kolasa T, et al. Symmetrical bis(heteroarylmethoxyphenyl)alkylcarboxylic acids as inhibitors of leukotriene biosynthesis. J Med Chem. 2000 Aug 24;43(17):3322-34. DOI:10.1021/jm000180n
Spectrum DetailBack Directory
[Spectrum Detail]

ABT 080(189498-57-5)1HNMR
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