Identification | Back Directory | [Name]
Epieriocalyxin A | [CAS]
191545-24-1 | [Synonyms]
Epieriocalyxin A Spiro[1H-7,9a-methanocyclohepta[c]pyran-4(3H),1'-[3]cyclohexene]-6'-carboxaldehyde, 4a,5,6,7,8,9-hexahydro-5',5',8-trimethyl-1,2',9-trioxo-, (1'S,4aS,6'R,7R,8R,9aS)- | [Molecular Formula]
C20H24O5 | [MDL Number]
MFCD20260394 | [MOL File]
191545-24-1.mol | [Molecular Weight]
344.4 |
Hazard Information | Back Directory | [Uses]
epi-Eriocalyxin A (Epieriocalyxin A), a diterpenoid isolated from Isodon eriocalyx, induces colon cancer apoptosis. epi-Eriocalyxin A also inhibits ERK1/2 and JNK activation, which suppresses Bcl-2 expression[1]. | [References]
[1] Zhou Wang, et al. Epieriocalyxin A Induces Cell Apoptosis Through JNK and ERK1/2 Signaling Pathways in Colon Cancer Cells. Cell Biochem Biophys. 2015 Nov;73(2):559-564. DOI:10.1007/s12013-015-0687-4 |
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