| Identification | Back Directory | [Name]
Desoxypodophyllotoxin | [CAS]
19186-35-7 | [Synonyms]
anthric
Nsc403148
Desoxypodophyllotoxin
4-Deoxypodophyllotoxin
(-)-Desoxypodophyllotoxin
Anthricin/Deoxypodophyllotoxin
Podophyllotoxin 9-Desoxy Impurity
Deoxypodophyllotoxin, deoxypodophyllotoxin
Furo[3',4':6,7]naphtho[2,3-D]-1,3-dioxol-6(5ah)-one, 5,8,8A,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-,(5R,5ar,8ar)- | [Molecular Formula]
C22H22O7 | [MDL Number]
MFCD01699018 | [MOL File]
19186-35-7.mol | [Molecular Weight]
398.41 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at 2-8°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [Boiling point ]
564.5±50.0 °C(Predicted) | [density ]
1.304±0.06 g/cm3(Predicted) | [form ]
Powder | [Melting point ]
168 °C | [color ]
White to off-white | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C22H22O7/c1-24-17-6-12(7-18(25-2)21(17)26-3)19-14-8-16-15(28-10-29-16)5-11(14)4-13-9-27-22(23)20(13)19/h5-8,13,19-20H,4,9-10H2,1-3H3/t13-,19+,20-/m0/s1 | [InChIKey]
ZGLXUQQMLLIKAN-SVIJTADQSA-N | [SMILES]
O1C2=CC3=C(C=C2OC1)[C@@H](C1=CC(OC)=C(OC)C(OC)=C1)[C@@]1([H])C(=O)OC[C@]1([H])C3 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless prismatic crystals (anhydrous ethanol), soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Sinopodophyllum hexandrum (Royle) Ying and Dysosma versipellis (Hance) M. Cheng ex Ying. | [Uses]
4-Deoxypodophyllotoxin is a medicinal herb product isolated from Anthriscus sylvestris Hoffm. It is well known for its antitumor, antiviral, and anti-inflammatory activities. 4-Deoxypodophyllotoxin wa
s also shown to inhibit the passive cutaneous anaphylaxis reaction. | [Definition]
ChEBI: A member of the class of furonaphthodioxoles that is (5R,5aR,8aR)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one substituted a
position 5 by a 3,4,5-trimethoxyphenyl group. | [in vivo]
Deoxypodophyllotoxin (intravenously injected; 5, 10, and 20 mg/kg; 3 times a week; 28 days) suppresses the tumors in a dose-dependent manner, the growth of tumors is inhibited by 22.19%, 47.91% and 50.93% with DPT at 5, 10 and 20 mg/kg, respectively[1]. | Animal Model: | Xenograft model of gastric cancer in nude mice with SGC-7901 cells[1] | | Dosage: | 5, 10, and 20 mg/kg | | Administration: | Intravenously injected; 5, 10, and 20 mg/kg; 3 times a week; 28 days | | Result: | Inhibited the growth of gastric cancer tumors. |
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| Company Name: |
cjbscvictory Gold
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| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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