| Identification | Back Directory | [Name]
Goserelin EP Impurity L ((D-Leu7)-Goserelin) | [CAS]
1926163-38-3 | [Synonyms]
Goserelin EP Impurity L
GoserelinEPImpurityL-Goserelin)
Goserelin EP Impurity L ((D-Leu7)-Goserelin)
Goserelin Impurity 12 （Goserelin EP Impurity L)
GoserelinEPImpurityLDiacetate-GoserelinDiacetate) | [Molecular Formula]
C59H84N18O14 | [MOL File]
1926163-38-3.mol | [Molecular Weight]
1269.41 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [pka]
9.82±0.15(Predicted) | [Sequence]
{Pyr}-His-Trp-Ser-Tyr-{d-Ser(tBu)}-{d-Leu}-Arg-Pro-{Azagly}-NH2 |
| Hazard Information | Back Directory | [Uses]
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1]. | [References]
[1] Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53. DOI:10.1073/pnas.232579499 |
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