| Identification | Back Directory | [Name]
Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate | [CAS]
193153-04-7 | [Synonyms]
FXV 673
Preluent
FXV673/FXV-673
OtaMixaban (FXV 673)
FXV 673; FXV673; FXV-673
Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate
Methyl (2R,3R)-2-{3-[aMino(iMino)Methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]aMino}butanoate
methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate
(αR)-3-(AMinoiMinoMethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester
[R-(R*,R*)]-3-(AMinoiMinoMethyl)-α-[1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester
Benzenepropanoic acid, 3-(aminoiminomethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]-, methyl ester, (αR)- | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C25H26N4O4 | [MDL Number]
MFCD11100277 | [MOL File]
193153-04-7.mol | [Molecular Weight]
446.5 |
| Chemical Properties | Back Directory | [density ]
1.25 | [storage temp. ]
Store at -20°C | [solubility ]
≥22.35 mg/mL in DMSO; insoluble in H2O; ≥55 mg/mL in EtOH with gentle warming | [form ]
Powder | [pka]
13.38±0.46(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
A potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Clinical studies show that it is efficacious
, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome. | [target]
Factor Xa |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
|