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1937-19-5

1937-19-5 Structure

1937-19-5 Structure
IdentificationMore
[Name]

AMINOGUANIDINE HYDROCHLORIDE
[CAS]

1937-19-5
[Synonyms]

amino-guanidinhydrochloride
hydrazinecarboximidamidehydrochloride
carbazamidine monohydrochloride
AMINOGUANIDINE HYDROCHLORIDE, 98+%
Aminoguanidine HCL
AMINOGUANIDINE SALT
GUANYLHYDRAZINEHCL
GUANIDINE,AMINO-,MONOHYDROCHLORIDE
Aminoguanidine hydrochoride
1-Aminoguanidine·hydrochloride
Aminoguanidine salts
[EINECS(EC#)]

217-707-7
[Molecular Formula]

CH7ClN4
[MDL Number]

MFCD00039074
[Molecular Weight]

110.546
[MOL File]

1937-19-5.mol
Chemical PropertiesBack Directory
[Appearance]

white to off-white crystals
[Melting point ]

162-166 °C(lit.)
[mp ]

162-166 °C(lit.)
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[form ]

Crystals
[color ]

White to off-white
[Merck ]

13,440
[BRN ]

3909606
[CAS DataBase Reference]

1937-19-5(CAS DataBase Reference)
[EPA Substance Registry System]

Hydrazinecarboximidamide, monohydrochloride (1937-19-5)
Questions And AnswerBack Directory
[Uses]

Aminoguanidine Hydrochloride is used in the synthetic preparation of highly selective and potent G-protein-coupled receptor kinase 2 (GRK2) inhibitor for potential treatment of heart failure.
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[RTECS ]

ME8430000
[F ]

10-21
[HS Code ]

29280000
Hazard InformationBack Directory
[Description]

Aminoguanidine is equipotent to L-NMMA and L-NNA as an inhibitor of iNOS. The IC50 values for inhibition of mouse iNOS and rat nNOS are 5.4 and 160 μM, respectively. Aminoguanidine also inhibits induction of iNOS protein expression by endotoxin in rat macrophages.
[Chemical Properties]

white to off-white crystals
[General Description]

Aminoguanidine hydrochloride has been reported in a study as inhibitor of animal nitric oxide (NO)-synthase. Crystal structure of aminoguanidine hydrochloride has been investigated by Fourier and least squares method. Its crystals were monoclinic and the guanidine part of the aminoguanidinium ion is planar.
[Biochem/physiol Actions]

Inhibits both constitutive and inducible nitric oxide synthetase.
Spectrum DetailBack Directory
[Spectrum Detail]

AMINOGUANIDINE HYDROCHLORIDE(1937-19-5)MS
AMINOGUANIDINE HYDROCHLORIDE(1937-19-5)IR1
AMINOGUANIDINE HYDROCHLORIDE(1937-19-5)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Aminoguanidine hydrochloride, 98%(1937-19-5)
[Sigma Aldrich]

1937-19-5(sigmaaldrich)
[TCI AMERICA]

Aminoguanidine Hydrochloride,>98.0%(T)(1937-19-5)
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